Gisou van der Goot research interests are focused on protein folding, protein-membrane interactions and signaling which her lab investigates through the study of bacterial toxins such as Anthrax toxin and their receptors on target cells. The role of palmitoylation in ER function and the mechanisms behind the compartimentalization of mamalian cells and cell membranes are other topics of interest.
With expertise in cell biology and biophysics, Aurélien Roux main research interest is to study the role of lipid membrane mechanical properties in several cell processes. His long-term goal is to understand how protein and lipid assemblies coordinate to perform cell functions involving membranes: endocytosis, cell division, cell migration and others.
Suliana Manley lab uses super-resolution fluorescence imaging techniques combined with live cell imaging and single molecule tracking to determine how the dynamics of protein assembly are coordinated. Her research interests include super-resolution fluorescence microscopy, high-density single molecule particle tracking, advanced fluorescence imaging, cellular imaging of protein and lipid transport and assembly.
The ultimate goal of Christian Heinis lab is the development of therapeutics by developing peptide macrocycles for potential therapeutic application using phase based strategy and biological and chemical tools. His lab currently develops potent antagonists to a range of disease targets, following medical indications in which bicyclic peptides promise advantages over small molecules and monoclonal antibodies.
His main research interests lie in understanding fundamental cell division processes, notably in the context of a developing organism and with a focus on the mechanisms governing centriole biogenesis and centrosome duplication as well as asymmetric cell division, a crucial phenomena for generating cellular diversity during development and in stem cell lineages.