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Dataset index

The NCCR Chemical Biology offers the following datasets as open source downloads:

 

2020

Dataset title: Homogeneous multifocal excitation for high-throughput super-resolution imaging – Expanded centriole particles
DOI: 10.5281/zenodo.3613906
Responsible person: Suliana Manley
Projects involved: 2
Article (2020)

 

Dataset title: Small-molecule modulators of the ATPase VCP/p97 affect specific p97 cellular functions
DOI: 10.5281/zenodo.3539008
Responsible person: Monica Gotta
Projects involved: 1
Article (2020)

 

Dataset title: High-content image-based drug screen identifies a clinical compound against cell transmission of adenovirus
Data: IDR Open microscopy
Responsible person: Fanny Georgi
Projects involved: ACCESS
Article (2020)

 

Dataset title: Mechanosensitive Membrane Probes: Push-Pull Papillons
DOI: 10.26037/yareta:5b2y3rzii5hufg6hpled2yyrlm
Responsible person: Stefan Matile
Projects involved: 4
Article (2020)

 

Dataset title: Anisotropic ESCRT-III architecture governs helical membrane tube formation
Electron Microscopy Data Bank: EMD-10136, EMD-10137, EMD-10138, EMD-10139
Responsible person: Aurélien Roux
Projects involved: 3
Article (2020)

 

Dataset title: An ESCRT-III polymerization sequence drives membrane deformation and fission
DOI: 10.5281/zenodo.3878199
Responsible person: Aurélien Roux
Projects involved: 3

 

Dataset title: Luciferase-Induced Photouncaging: Bioluminolysis
DOI: 10.5281/zenodo.3374180
Responsible person: Nicolas Winssinger
Projects involved: 1
Article (2020)

 

Dataset title: Caprin-1 promotes cellular uptake of nucleic acids with backbone and sequence discrimination
DOI: 10.26037/yareta:grrtg4elinhphfldoeto5rwhpy
Responsible person: Aurélien Roux
Projects involved: 4
Article (2020)

 

Dataset title: Buckling of epithelium growing under spherical confinement Trushko et al.
DOI: 10.17632/3vfxhr2m34.1
Responsible person: Aurélien Roux
Projects involved: 3
Article (2020)

 

Dataset title: Probing for Thiol-Mediated Uptake into Bacteria
DOI: 10.5281/zenodo.3336270
Responsible person: Stefan Matile
Projects involved: 4
Article (2020)

 

Dataset title: Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems such as Adaptive Benzopolysulfane Networks
DOI: 10.26037/yareta:v7airh7g7rfrlpa3s7m64unefy
Responsible person: Stefan Matile
Projects involved: 4, 5
Article (2020)

 

Dataset title: Next generation sequencing data for phage selection against FXIa
DOI: 10.6084/m9.figshare.11921139.v2
Responsible person: Christian Heinis
Projects involved: 1
Article (2020)

 

Dataset title: Computational design of anti-CRISPR proteins with improved inhibition potency and expanded specificity
Link: https://github.com/LPDI-EPFL
Responsible person: Bruno Correia
Projects involved: 2
Article (2020)

 

Dataset title: Smartphone DNA or RNA-Sensing Using Semisynthetic Luciferase-Based Logic Device
DOI: 10.5281/zenodo.3689190
Responsible person: Nicolas Winssinger
Projects involved: 1
Article (2020)

 

Dataset title: PNA-Based Dynamic Combinatorial libraries (PDCL) and screening of lectins
DOI: 10.5281/zenodo.3712677
Responsible person: Nicolas Winssinger
Projects involved: 1
Article (2020)

 

Dataset title: PRM of Nth1 phospho-peptides in response to AGC-kinase inhibition
Data: PRM data have been deposited at Panorama Public: https://panoramaweb.org/wMKBjd.url and are accessible at ProteomeXchange via identifier PXD015760.
Responsible person: Robbie Loewith
Projects involved: 1
Article (2020)

 

Dataset title: Chemical genetics of AGC-kinases reveals shared targets of Ypk1, Protein Kinase A and Sch9
DOI: 10.6084/m9.figshare.11474685
Responsible person: Robbie Loewith
Projects involved: 1
Article (2020)

 

Dataset title: Yeast AGC-kinases phospho-proteomics
Data: DDA data have been deposited to the ProteomeXchange Consortium via the PRIDEpartner repository with the data set identifier PXD015668 and 10.6019/PXD015668.
Spectra were additionally deposited to MS-Viewer and are accessible using key 99yh6tladc.
Responsible person: Robbie Loewith
Projects involved: 1
Article (2020)

 

Dataset title: Next generation sequencing data for phage selection against FXIa
DOI: 10.6084/m9.figshare.11921139.v2
Responsible person: Christian Heinis
Projects involved: 1
Article (2020)

 

2019

Dataset title: Fluorescent Flipper Probes: Comprehensive Twist Coverage
DOI: 10.26037/yareta:netxbo6p6rhvtaf2fjasfyvvkq
Responsible person: Stefan Matile
Projects involved: 4
Article (2019)

 

Dataset title: Methyl Scanning for Mechanochemical Chalcogen-Bonding Cascade Switches
DOI: 10.26037/yareta:5yjhzxle4ffzbfgjxebqmlulhq
Responsible person: Stefan Matile
Projects involved: 4
Article (2019)

 

Dataset title: Role of the mRNA-binding protein HuR in the global transcriptomic status of cells stimulated with electrophiles and oxidants
Data: RNA-Sequencing data are available at the Gene Expression Omnibus (GEO; accession number GSE127444); all other data are in supporting info.
Responsible person: Yimon Aye
Projects involved: 4
Article (2019)

 

Dataset title: A Chalcogen-Bonding Cascade Switch for Planarizable Push-Pull Probes
DOI: 10.5281/zenodo.3369793
Responsible person: Stefan Matile
Projects involved: 4
Article (2019)

 

Dataset title: Coupling of DNA Circuit and Templated Reactions for Quadratic Amplification and Release of Functional Molecules
DOI: 10.5281/zenodo.3337874
Responsible person: Nicolas Winssinger
Projects involved: 1
Article (2019)

 

Dataset title: “Doubly Orthogonal” Labeling of Peptides and Proteins
DOI: 10.5281/zenodo.3246280
Responsible person: Beat Fierz
Projects involved: 3, 4
Article (2019)

 

Dataset title: Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging
DOI: 10.5281/zenodo.1475055
Responsible person: Suliana Manley
Projects involved: 2
Article (2019)

 

Dataset title: Cell-Penetrating Dynamic-Covalent Benzopolysulfane Networks – Raw data
DOI: 10.5281/zenodo.3044493
Responsible person: Stefan Matile
Projects involved: 4
Article (2019)

 

2018

 

Dataset title: SPARTAN example data
DOI: 10.5281/zenodo.1288783
Responsible person: Suliana Manley
Projects involved: 2, 3
Article (2018)

 

Dataset title: LUPIN
DOI: 10.5281/zenodo.1312221
Responsible person: Nicolas Winssinger
Projects involved: 1
Article (2018)