Frei M.S., Hoess P., Lampe M., Nijmeijer B., Kueblbeck M., Ellenberg J., Ries J., Pitsch S., Reymond L., Johnsson K., “Photoactivation of silicon rhodamines via a light-induced protonation”, bioRxiv, 626853, 2019. Open access [More Information]

Kale S.S., Bergeron-Brlek M., Wu Y., Kumar M.G., Pham M.V., Bortoli J., Vesin J., Kong X.D., Machado J.F., Deyle K., Gonschorek P., Turcatti G., Cendron L., Angelini A., Heinis C., “Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands”, Science Advances, 5, eaaw2851. Open access [More Information]

Moreau D, Vacca F, Vossio S, Scott C, Colaco A, Paz Montoya J, Ferguson C, Damme M, Moniatte M, Parton RG, Platt FM, Gruenberg J., “Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice”, EMBO Rep., 2019 May 22. Open access [More Information]

Vacca F., Vossio S., Mercier V., Moreau D., Johnson S., Scott C.C., Paz Montoya J., Moniatte M., Gruenberg J., “Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells“, J. Lipid Res., pii: jlr.M089979, doi: 10.1194/jlr.M089979, 2019. Free access from April 2020 [More Information]

Mayya Sundukova, Efthymia Prifti, Annalisa Bucci, Kseniia Kirillova, Joana Serrao, Luc Reymond, Miwa Umebayashi, Ruud Hovius, Howard Riezman, Kai Johnsson, Paul A. Heppenstall, “A Chemogenetic Approach for the Optical Monitoring of Voltage in Neurons”, Ang. Chemie, 58, 8, 2019. Open access [More Information]

Bazhin A. A., Chambon M., Vesin J., Bortoli J., Collins J. W., Turcatti G., Chou C. J., Goun E. A., “A Universal Assay for Aminopeptidase Activity and Its Application for Dipeptidyl Peptidase-4 Drug Discovery”, Analytical Chemistry 91, 1098-1104, 2019. [More Information]

Varbanov H. P., Kuttler F., Banfi D., Turcatti G., Dyson P. J., “Screening-based approach to discover effective platinum-based chemotherapies for cancers with poor prognosis”, PLOS ONE 14, e0211268, 2019. Open access [More Information]

Martins Lima, A.; Bragina, M. E.; Burri, O.; Bortoli Chapalay, J.; Costa-Fraga, F. P.; Chambon, M.; Fraga-Silva, R. A.; Stergiopulos, N., “An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format”, Platelets, 1-9, 2018. [More Information]

Haag S.M., Gulen M.F., Reymond L., Gibelin A., Abrami L., Decout A., Heymann M., van der Goot F.G., Turcatti G., Behrendt R., Ablasser  A., “Targeting STING with covalent small-molecule inhibitors”, Nature volume 559, 269–273, 2018. [More Information]

Dhandapani, Rahul; Arokiaraj, Cynthia Mary; Taberner, Francisco J.; Pacifico, Paola; Raja, Sruthi; Nocchi, Linda; Portulano, Carla; Franciosa, Federica; Maffei, Mariano; Hussain, Ahmad Fawzi; de Castro Reis, Fernanda; Reymond, Luc; Perlas, Emerald; Garcovich, Simone; Barth, Stefan; Johnsson, Kai; Lechner, Stefan G.; Heppenstall, Paul A., “Control of Mechanical Pain Hypersensitivity in Mice through Ligand-Targeted Photoablation of TrkB-Positive Sensory Neurons”, Nature Communications, 9(1):1640, 2018. [More Information]