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Paul Dyson

Chemical Sciences and Engineering, EPFL

  • Full Professor
  • Associated member of the NCCR Chemical Biology

About

Paul Dyson joined the Institute of Chemical Sciences and Engineering at the EPFL in 2002 where he heads the Laboratory of Organometallic and Medicinal Chemistry and from 2008 has chaired the Institute. In recent years has held visiting professorships at the University of Bourgogne, University of Pierre et Marie Curie, University of Vienna, University of Rome Tor Vergara and Chimie Paristech. He is currently a guest professor at Shangai Jiao Tong University (2012-2015).

His main research interests are in bioorganometallic chemistry and the study of metal ions in living systems. He has developed a series of organometallic drugs that display in vivo antimetastatic and antiangiogenic properties. He has also developed a range of mass spectrometry based methods to determine metal-drug targets from whole cell systems and to elucidate the mode and site of metal binding on target proteins.

He has also won several prizes including the Werner Prize of the Swiss Chemical Society in 2004, the Award for Outstanding Achievements in Bioorganometallic Chemistry in 2010, the Centennial Luigi Sacconi Medal 2011 of the Italian Chemical Society and The Bioinorganic Chemistry Award of the Royal Society of Chemistry in 2015.

Read more about Paul Dyson’s research on his lab website.

Contact

Ecole polytechnique fédérale de Lausanne
Institut des sciences et ingénierie chimiques
EPFL SB ISIC LCOM
BCH 2402 (Batochime)
1015 Lausanne, Switzerland
Phone: +41 (0)21 693 98 54
E-mail: paul.dyson@epfl.ch

Publications

Gabriela E. Davey, Zenita Adhireksan, Zhujun Ma, Tina Riedel, Deepti Sharma, Sivaraman Padavattan, Daniela Rhodes, Alexander Ludwig, Sara Sandin, Benjamin S. Murray, Paul J. Dyson, Curt A. Davey, “Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation”, Nature Communications 8, 2017. [More Information]