Marko Kaksonen

Department of Biochemistry

Professor of Biochemistry
Principal Investigator: Project 3: Imaging mechanical forces in living systems

About Marko Kaksonen

Marko Kaksonen is a professor in the Department of Biochemistry at the University of Geneva. His lab studies the molecular mechanisms of clathrin-mediated endocytosis. The lab develops and uses light and electron microscopy methods for quantitative visualization of cellular trafficking processes.

Read more about Marko Kaksonen’s research on his lab website.

Contact

University of Geneva
Department of Biochemistry
30, Quai Ernest-Ansermet
1211, Geneva 4, Switzerland
Phone : +41 (0)22 379 69 97
Email: [email protected]

Projects

Project 3: Imaging mechanical forces in living systems

Publications

Project 3: Imaging mechanical forces in living systems

Christopher Toret, Andrea Picco, Micaela Boiero-Sanders, Alphee Michelot, Marko Kaksonen, “The cellular slime mold Fonticula alba forms a dynamic, multicellular collective while feeding on bacteria”, Current Biology, Volume 32, Issue 9, 2022. [More Information]

Project 3: Imaging mechanical forces in living systems

Mateusz Kozak, Marko Kaksonen, “Condensation of Ede1 promotes the initiation of endocytosis”, eLife 11:e72865, 2022. Open access [More Information]

Project 3: Imaging mechanical forces in living systems

Del Signore SJ, Kelley CF, Messelaar EM, Lemos T, Marchan MF, Ermanoska B, Mund M, Kaksonen M, Rodal AA., “Autoregulation clamps the synaptic membrane-remodeling machinery and promotes productive actin-dependent endocytosis”, bioRxiv, 2020 [More Information]

Project 3: Imaging mechanical forces in living systems

Kozak M, Kaksonen M., “Phase separation of Ede1 promotes the initiation of endocytic events”, bioRxiv, 2019. [More Information]

Project 3: Imaging mechanical forces in living systems

Manenschijn H.E., Picco A., Mund M., Ries J., Kaksonen M., “Type-I myosins promote actin polymerization to drive membrane bending in endocytosis”, eLife 2019;8:e44215, DOI: 10.7554/eLife.44215. Open access [More Information]

Project 3: Imaging mechanical forces in living systems

Picco A., Kukulski W., Manenschijn H.E., Specht T., Briggs J.A.G., Kaksonen M., “The contributions of the actin machinery to endocytic membrane bending and vesicle formation”, Mol. Biol. Cell, doi.org/10.1091/mbc.E17-11-0688, 2018. [More Information]

Project 3: Imaging mechanical forces in living systems

Picco, A., Kaksonen, M. “Quantitative imaging of clathrin-mediated endocytosis”, Curr. Opin. Cell Biol., 2018. [More Information]

Project 3: Imaging mechanical forces in living systems

Mund M, van der Beek, JA, Deschamps J, Dmitrieff S, Hoess, P, Monster JL, Picco A, Nedelec F, Kaksonen M, Ries J., “Systematic nanoscale analysis of endocytosis links efficient vesicle formation to patterned actin nucleation”, Cell, 884-896.e17, 2018. Open access [More Information]

Project 3: Imaging mechanical forces in living systems

Kaksonen M., Roux A., “Mechanisms of clathrin-mediated endocytosis”, Nat. Rev. Mol. Cell. Biol. 2018, doi: 10.1038/nrm.2017.132. [More Information]

Project 3: Imaging mechanical forces in living systems

Picco, A., Irastroza-Azcarate, I., Specht, T., Böke, D., Pazos, I., Rivier- Cordey, A. S., Devos, D., Kaksonen, M., Gallego, O., “The in vivo architecture of the exocyst provides a structural basis for exocytosis”, Cell 168, 400-412, 2017. [More Information]

Project 3: Imaging mechanical forces in living systems

Kukulski W., Picco A., Specht T., Briggs JA., Kaksonen M. “Clathrin modulates vesicle scission, but not invagination shape, in yeast endocytosis”. Elife. (2016), pii: e16036. [More Information]