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Marcos Gonzalez Gaitan

Marcos Gonzalez Gaitan

Biochemistry Department, University of Geneva

About Marcos Gonzalez Gaitan

Marcos Gonzalez Gaitan did his PhD in Madrid with Antonio Garcia-Bellido and a postdoc with Herbert Jäckle in Göttingen. Then he started his group in the Max-Planck Institute of molecular cell biology and genetics in Dresden. His initial focus was on the Cell Biology of Development: endocytosis, signaling, morphogens. Then he started to collaborate with the Jülicher group from the MPI of Physics of complex systems. Since then, his strength is to combine developmental molecular biology, cell biology and physics. Marcos Gonzalez-Gaitán is a professor in biochemistry at the University of Geneva.

His main research interest is the biophysics and cell biology of endocytic trafficking during morphogenetic signalling and asymmetric cell division, to understand how cells talk to each other during development in physical and molecular terms and how the shape and final size of a tissue is achieved during embryogenesis. His approach is highly multidisciplinary and is performed in two model systems: Drosophila and Zebrafish.

Read more about Marcos Gonzalez Gaitan’s research on his lab website.


University of Geneva
Department of Biochemistry
30, quai Ernest-Ansermet
CH-1211, Geneva 4, Switzerland
Phone (lab): +41 (0)22 379 6497



Assies Lea, García-Calvo José, Piazzolla Francesca, Sanchez Samantha, Kato Takehiro, Reymond Luc, Goujon Antoine, Colom Adai, López-Andarias Javier, Straková Karolína, Mahecic Dora, Mercier Vincent, Riggi Margot, Jiménez-Rojo Noemi, Roffay Chloé, Licari Giuseppe, Tsemperouli Maria, Neuhaus Frederik, Fürstenberg Alexandre, Vauthey Eric, Hoogendoorn Sascha, Gonzalez-Gaitan Marcos, Zumbuehl Andreas, Sugihara Kaori, Gruenberg Jean, Riezman Howard, Loewith Robbie, Manley Suliana, Roux Aurelien, Winssinger Nicolas, Sakai Naomi, Pitsch Stefan, Matile Stefan, “Flipper probes for the community”, CHIMIA International Journal for Chemistry, Volume 75, Number 12, 2021. Open access [More Information]

Rajwinder Lehal, Jelena Zaric, Michele Vigolo, Charlotte Urech, Viktoras Frismantas, Nadine Zangger, Linlin Cao, Adeline Berger, Irene Chicote, Sylvain Loubéry, Sung Hee Choi, Ute Koch, Stephen C. Blacklow, Hector G. Palmer, Beat Bornhauser, Marcos González-Gaitán, Yvan Arsenijevic, Vincent Zoete, Jon C. Aster, Jean-Pierre Bourquin, and Freddy Radtke, “Pharmacological disruption of the Notch transcription factor complex”, PNAS 117 (28) 16292-16301, 2020. [More Information]

Castanon I., Hannich J.T., Abrami L., Huber F., Dubois M., Müller M., van der Goot F., Gonzalez-Gaitan M., “Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish”, 11, Article number: 3317, 2020. Open access. Dataset info [More Information]

Javier López-Andarias, Jacques Saarbach, Dimitri Moreau, Yangyang Cheng, Emmanuel Derivery, Quentin Laurent, Marcos González-Gaitán, Nicolas Winssinger, Naomi Sakai, Stefan Matile, “Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks”, J. Am. Chem. Soc. 2020, 142, 10, 4784-4792. Open accessDataset info Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems such as Adaptive Benzopolysulfane Networks“.  [More Information]

Bartolami E., Basagiannis D., Zong L., Martinent R., Okamoto Y., Laurent Q., Ward T. R., Gonzalez-Gaitan M., Sakai N., Matile S.,  “Diselenolane-Mediated Cellular Uptake: Efficient Cytosolic Delivery of Probes, Peptides, Proteins, Artificial Metalloenzymes and Protein-Coated Quantum Dots,” Chem. Eur. J. 2019, 25, 4047–4051. [More Information]

Holtzer L., Oleinich I., Anzola M., Sadhu K.K., Gonzalez-Gaitan M., Winssinger N., “Nucleic-acid templated chemical reaction in a live vertebrate”, ACS Central Science, (2016), 2 (6), 394-400. Press release by UNIGE and NCCR Chemical Biology. [More Information]

Romanova-Michaelidis M., Aguilar-Hidalgo D., Jülicher F., González-Gaitán M. “The wing and the eye: a parsimonious theory for scaling and growth control?” Wiley Interdisciplinary Reviews: Developmental Biology. Volume 4, Issue 6, pages 591–608, (November/December 2015). [More Information]

Dal Molin M., Verolet Q., Colom A., Letrun R., Derivery E., Gonzalez-Gaitan M., Vauthey E., Roux A., Sakai N., Matile S. “Fluorescent Flippers for Mechanosensitive Membrane Probes”, J. Am. Chem. Soc., 137, 568-571, (2015). [More Information]