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Elena Goun

Chemical Sciences and Engineering, EPFL

  • Assistant Professor (tenure-track)

About

Elena Goun has been appointed Tenure Track Assistant Professor of bio-organic chemistry at the School of Basic Sciences (FSB). She received her MS degree from University of Central Florida. She continued her PhD studies in the field of medicinal chemistry and drug delivery in the group of Professor Paul Wender at Stanford University. After graduation with a PhD degree in 2008, she moved to University of California at Berkeley where she did her postdoctoral studies in the field of Chemical Biology in the group of Carolyn Bertozzi.

Elena Goun develops new tools to study important biological processes in metabolic diseases such as determination of beta-cell mass, understanding functions of uncoupling proteins (UCPs), and imaging brown adipose tissues (BAT). Discover new bioorthogonal reactions and their applications to image small ligand receptor interactions in various disease settings. She also synthesizes probes for image guided surgery and diagnostic in cancer, with collaborators. She is an advocate of an interdisciplinary approach, combining synthetic chemistry, optical imaging, and an understanding of cellular functions at molecular level to find solutions to fundamental problems in biology and medicine. She performs her research work in the context of the new Chair in biological chemistry, at EPFL’s Institute of Chemical Sciences and Engineering.

Read more about Elena Goun’s research on her lab website.

Contact

Ecole polytechnique fédérale de Lausanne
Institut des sciences et ingénierie chimiques
EPFL SB ISIC LCBIM
BCH 5307 (Bâtochime)
1015 Lausanne, Switzerland
Phone: +41 (0)21 693 93 04
Email: [email protected]

Publications

Tamara Maric, Georgy Mikhaylov, Pavlo Khodakivskyi, Arkadiy Bazhin, Riccardo Sinisi, Nicolas Bonhoure, Aleksey Yevtodiyenko, Anthony Jones, Vishaka Muhunthan, Gihad Abdelhady, David Shackelford & Elena Goun, “Bioluminescent-based imaging and quantification of glucose uptake in vivo”, Nature Methods volume 16, pages 526–532, 2019. Free access from November 2019 [More Information]

Godinat A., Bazhin A.A., Goun E.A., “Bioorthogonal chemistry in bioluminescence imaging”, Drug Discov. Today, pii: S1359-6446(17)30591-3. doi: 10.1016/j.drudis.2018.05.022, 2018. [More Information]

Vorobyeva A.G., Stanton M., Godinat A., Lund K.B., Karateev G.G., Francis K.P., Allen E., Gelovani G.J., McCormack E., Tangney M., Dubikovskaya E.A., “Development of a Bioluminescent Nitroreductase Probe for Preclinical Imaging”, PloS ONE, 2015. Open access [More Information]