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Andreas Zumbühl

Department of Chemistry

  • Professor


Andreas Zumbühl is a Professeur Boursier in the Department of Chemistry at the University of Fribourg. His main research interests are the synthesis of artificial phospholipids and their applications in biology and medicine. His current project is on approaches for non-spherical and surface-activated liposomes.

Read more about Andreas Zumbühl’s research on his lab website.


University of Fribourg
Department of Chemistry
Chemin du Musée 9
1700 Fribourg, Switzerland
Phone: +41 (0)26 300 8794


J. Thomas Hannich, A. Galih Haribowo, Sébastien Gentina, Melanie Paillard, Ludovic Gomez, Bruno Pillot, Hélène Thibault, Daniel Abegg, Nicolas Guex, Andreas Zumbuehl, Alexander Adibekian, Michel Ovize, Jean-Claude Martinou & Howard Riezman, “1-Deoxydihydroceramide causes anoxic death by impairing chaperonin-mediated protein folding”, Nature Metabolism volume 1, pages996–1008, 2019. [More Information]

Neuhaus, F.; Mueller, D.; Tanasescu, R.; Stefaniu, C.; Zaffalon, P. L.; Balog, S.; Ishikawa, T.; Reiter, R.; Brezesinski, G.; Zumbuehl, A., “Against the rules: pressure induced transition from high to reduced order”, Soft Matter, 14 (19), 3978-3986, 2018. [More Information]

Neuhaus, F.; Mueller, D.; Tanasescu, R.; Balog, S.; Ishikawa, T.; Brezesinski, G.; Zumbuehl, A., “Synthesis and Biophysical Characterization of an Odd-Numbered 1,3-Diamidophospholipid”, Langmuir, 34 (10), 3215–3220, 2018. [More Information]

Sofiya Matviykiv, Marzia Buscema, Gabriela Gerganova, Tamás Mészáros, Gergely Tibor, Kozma, Ute Mettal, Frederik Neuhaus, Takashi Ishikawa, János Szebeni, Andreas Zumbuehl, Bert Müller, “Immunocompatibility of Rad-PC-Rad liposomes in vitro, based on human complement activation and cytokine release”, Prec. Nanomed. 2018 Apr;1(1):43-62. Open access [More Information]

Radu Tanasescu,  Ute Mettal, Adai Colom, Aurélien Roux and Andreas Zumbuehl, “Facile and rapid Formation of Giant Vesicles from Glass Beads”, Polymers, 10(1), 54; doi:10.3390/polym10010054, 2018. [More Information]

Neuhaus F., Zobi F., Brezesinski G., Dal Molin M., Matile S., Zumbuehl A.,  “Correlation of Surface Pressure and Color Hue of Planarizable Push-Pull Chromophores at the Air/Water Interface”, Beilstein J. Org. Chem. 2017, 13, 1099–1105. [More Information]

Hannich J. T., Mellal D., Feng S., Zumbuehl A., Riezman H., “Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegans”, Chem. Sci., 2017, 8, 3676-3686. [More Information]

Neuhaus F., Mueller D., Tanasescu R., Balog S., Ishikawa T., Brezesinski G., Zumbuehl A., “Vesicle Origami: Cuboid Phospholipid Vesicles Formed by Template-Free Self-Assembly”, Angew. Chem. Int. Ed., 2017, 56, 6515. [More Information]

Tanasescu R., Lanz M., Mueller D., Tassler S., Ishikawa T., Reiter R., Brezesinski G., Zumbuehl A., “Vesicle Origami and the Influence of Cholesterol on Lipid Packing”, Langmuir, (2016), 32, 4896-4903. [More Information]

Weinberger A., Tanasescu R., Stefaniu C., Fedotenko I., Favarger F., Ishikawa T., Brezesinski G., Marques C., Zumbuehl A., 
”Bilayer Properties of 1,3-Diamidophospholipids”. Langmuir 31, 1879-1884, (2015). [More Information]

Stefaniu C., Zaffalon P.L., Carmine A., Verolet Q., Fernandez S., Wesolowski T.A., Brezesinski G., Zumbuehl A. 
”Rigid Urea and Self-Healing Thiourea Ethanolamine Monolayers”
, Langmuir  31, 1296-1302, (2015). [More Information]