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Prof. Yimon Aye receives the 2022 Tetrahedron Young Investigator Award

We are very proud of Prof. Yimon Aye, NCCR Chemical Biology member, who has been selected for the Tetrahedron Young Investigator Award 2022 for Bioorganic and Medicinal Chemistry.

The Tetrahedron Young Investigator Awards were created in 2005 by the Executive Board of Editors and the Publisher of Tetrahedron Publications. Awards are presented to two individuals under the age of 40 who have exhibited “exceptional creativity and dedication” in the fields of Organic Synthesis and of Bioorganic and Medicinal Chemistry respectively.

As part of the award, which has a monetary award of $3000 for each winner,  awardees are invited to deliver a plenary lecture at the forthcoming Tetrahedron Symposium in 2022, where they will be formally presented with their award. Furthermore, two special issues will be compiled in their honour. Like the Tetrahedron Prize for Creativity in Organic Chemistry, which these awards complement, the Tetrahedron Young Investigator Awards are bestowed on an annual basis.

Each award has a separate voting committee, with the Editors of Tetrahedron and Tetrahedron Letters voting on the Organic Synthesis Award, and the Editors of Bioorganic and Medicinal Chemistry and Bioorganic and Medicinal Chemistry Letters, voting on the Bioorganic and Medicinal Chemistry Award.

Yimon Aye received a training at the frontiers of small-molecule chemistry and mechanistic biology which endowed her with a unique, cross-disciplinary vision. Born and raised in Burma, Yimon Aye achieved her undergraduate and PhD degrees in Chemistry and Organic Chemistry at Oxford (UK) and Harvard (USA). During her postdoc training at MIT (USA), she studied the regulatory mechanisms of the enzyme ribonucleotide reductase. In her independent career that began mid-2012, Yimon Aye set out to understand the detailed mechanisms of electrophile signaling. This impetus culminated in the development of “REX” technologies (T-REX™ delivery and G-REX™ profiling). In a parallel research program, Yimon Aye studies pathways involved in genome maintenance and nucleotide signaling, including the mechanisms of anticancer drugs in clinical use.

As of August 2018, Prof. Yimon Aye is leading the Laboratory of Electrophiles And Genome Operation (LEAGO) at ISIC, EPFL (Switzerland) as a tenured associate professor. Yimon Aye joined the NCCR Chemical Biology in 2018 as a principal investigator. She is deputy co-Director of the NCCR Chemical Biology and member of the NCCR steering committee.

Previous recipients of the Tetrahedron Young Investigator Awards

  • 2021: Guangbin Dong, Organic Synthesis;
    Neal Devaraj, Bioorganic and Medicinal Chemistry
  • 2020: Nuno Maulide, Organic Synthesis;
    Emily Balskus, Bioorganic and Medicinal Chemistry
  • 2019: Ryan Shenvi, Organic Synthesis;
    Raphaël Rodriguez, Bioorganic and Medicinal Chemistry
  • 2018: Seth Herzon, Organic Synthesis;
    Matthew Fuchter, Bioorganic and Medicinal Chemistry
  • 2017: Ang Li, Organic Synthesis;
    Xiaoguang Lei, Bioorganic and Medicinal Chemistry
  • 2016: Neil Garg, Organic Synthesis;
    Matthew Disney, Bioorganic and Medicinal Chemistry
  • 2015: Yoshiaki Nakao, Organic Synthesis;
    Maja Köhn, Bioorganic and Medicinal Chemistry
  • 2014: Sarah E. Reisman, Organic Synthesis;
    Rudi Fasan, Bioorganic and Medicinal Chemistry
  • 2013: Melanie Sanford, Organic Synthesis;
    Ashraf Brik, Bioorganic and Medicinal Chemistry
  • 2012: Zhang-Jie Shi, Organic Synthesis;
    B.G. Davis, Bioorganic and Medicinal Chemistry
  • 2011: F. Dean Toste, Organic Synthesis;
    Carolyn R. Bertozzi, Bioorganic and Medicinal Chemistry
  • 2010: Brian Stoltz, Organic Synthesis;
    Peter Seeberger, Bioorganic and Medicinal Chemistry
  • 2009: Michael Krische, Organic Synthesis;
    Carlos Barbas, Bioorganic and Medicinal Chemistry
  • 2008: Justin du Bois, Organic Synthesis;
    Benjamin Cravatt, Bioorganic and Medicinal Chemistry
  • 2007: John Hartwig, Organic Synthesis;
    Wilfred van der Donk, Bioorganic and Medicinal Chemistry
  • 2006: Erick Carreira, Organic Synthesis;
    Jon Ellman, Bioorganic and Medicinal Chemistry
  • 2005: David MacMillan, Organic Synthesis;
    Laura Kiessling, Bioorganic and Medicinal Chemistry