Heart attack and tissue damage: the missing link is a lipid
Major breakthrough published in Nature Metabolism today. Discovery of the molecule responsible for tissue necrosis due to an infarct, and how to reduce tissue damage by 30% in mice!
New health research shines a light on ‘circadian clock’ at work in our muscles
Researchers funded by the SNSF have discovered a biological clock at work in our muscle cells. It could be a factor in regulating our metabolism and play a role in diabetes.
Structure and conserved function of iso-branched sphingoid bases from the nematode C. elegans
The collaborative efforts of two NCCR groups, the Riezman lab and the Zumbühl group, were recently reported in Chemical Science.
A new method to detect cholesterol
A research team from the UNIGE / NCCR Chemical Biology, in collaboration with the Universities of California and Helsinki, has created a natural cholesterol that can be detected in the body.
Sphingosine role in calcium homeostasis
The collaborative efforts of several groups across the globe, including the Riezman lab from UNIGE and member of the NCCR network, were recently reported in e-Life journal.
New light on anti-sphingolipid targeting cancer therapy
NCCR researchers and other external labs identify the lysosomal transmembrane protein, LAPTM4B, as a specific ceramide binding protein and an alternative regulator of ceramide clearance from the late endosomes independently of the known ceramidase-dependent catabolism.
Best poster awards – NCCR retreat
The best three posters were elected by a jury presided by NCCR director Howard Riezman.
Publication of the groups Riezman & Johnsson (ACS)
When a scientist labels a membrane protein with a dye, she has to wash the cells a few times to […]
Publication of Howard Riezman & group in Cell Reports
The goal of this study was to identify mechanisms that regulate the rate of VLCFA synthesis, and we discovered that the fatty acid elongase Elo2 is regulated by phosphorylation.
A new NCCR publication in Cell Reports
The Riezman lab show a mechanism that allows organisms to tolerate specific nutrients and adapt to available resources.
