New DNA stain lights up living cells
EPFL scientists have now developed a new DNA stain that can be used to safely image live mammalian cells for days, even under demanding imaging conditions.
New light on anti-sphingolipid targeting cancer therapy
NCCR researchers and other external labs identify the lysosomal transmembrane protein, LAPTM4B, as a specific ceramide binding protein and an alternative regulator of ceramide clearance from the late endosomes independently of the known ceramidase-dependent catabolism.
The light of fireflies for medical diagnostics
NCCR scientists at EPFL have exploited the light of fireflies in a new method that detects biological molecules without the need for complex devices and high costs.
How a protein regulates gene expression
Prof. Beat Fierz’s group at NCCR EPFL have discovered how specialized proteins control gene expression by binding and compacting discrete parts of DNA inside the cell.
Structure & function of the protein kinase Target Of Rapamycin Complex 2
Their study, published in the journal Molecular Cell, describes the structure of TORC2 and explains why rapamycin cannot access the TOR protein in this complex.
Bromodomains epigenetic readers
Bromodomains are important actors in epigenetic regulation. They represent small domains of about 110 amino acids that dock onto chromatin bearing acetylated lysine histone tails.
EPFL scientists have developed a new amino acid
The team of Christian Heinis at EPFL has developed a synthetic amino acid whose unique structure can considerably increase the effectiveness of therapeutic peptides and proteins.
A new molecule for high-resolution cell imaging
EPFL scientists have developed novel fluorescent probes for imaging these important structures easily and with unprecedented resolution.
Aurélien Roux published a review in Cell
Congratulations to Aurélien Roux who published a review in Cell this February.
Publication of the groups Riezman & Johnsson (ACS)
When a scientist labels a membrane protein with a dye, she has to wash the cells a few times to […]
