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Diversity of DNA-encoded synthetic molecules through mating

Published in Nature Chemistry, the article describes a new technique for selecting assemblies of small molecules through programmed assembly using DNA-pairing processes, making it possible to find the best combinations for each protein to be combated, quickly and cheaply.

Mitochondrial membrane tension governs fission

The NCCR Chemical Biology is proud to announce a new open access publication in Cell Reports stemming from the collaboration of 3 NCCR labs (Manley, Roux and Matile). Interdisciplinary collaboration strikes again!

Tracking proteins in the heart of cells

An interdisciplinary team of NCCR members has been able to follow precisely the path taken by a motor protein in cells, paving the way for the study of the transport activity and distribution of cargoes in cells.

A sulfur molecule to block the coronavirus

Some viruses can get inside cells via a mechanism that involves sulfur organic molecules. An NCCR team has discovered effective inhibitors and blocked the uptake of SARS-CoV-2.

endoplasmic reticulum and nuclear envelope

The physical forces of cells in action

Hot from the press of JACS! Mechanosensitive fluorescent probes to Image membrane tension in mitochondria, endoplasmic reticulum & lysosomes! Congrats to our NCCR groups who made it happen!