Multilayered omics highlight adipose progenitor cell heterogeneity
The NCCR Chemical Biology is proud to announce a new open access publication in Cell Metabolism stemming from the new Proteomics platform at UNIGE.
Our signature accomplishments on membranes and cell signaling highlighted today in Chimia
Discover some of our key accomplishments on membranes and how they impact cellular signaling. An adventure that started eleven years ago!
Motor usage imprints microtubule stability along the shaft
The collaborative work conducted between the Aumeier and Kruse labs is reported in Developmental Cell.
Diversity of DNA-encoded synthetic molecules through mating
Published in Nature Chemistry, the article describes a new technique for selecting assemblies of small molecules through programmed assembly using DNA-pairing processes, making it possible to find the best combinations for each protein to be combated, quickly and cheaply.
Mitochondrial membrane tension governs fission
The NCCR Chemical Biology is proud to announce a new open access publication in Cell Reports stemming from the collaboration of 3 NCCR labs (Manley, Roux and Matile). Interdisciplinary collaboration strikes again!
Tracking proteins in the heart of cells
An interdisciplinary team of NCCR members has been able to follow precisely the path taken by a motor protein in cells, paving the way for the study of the transport activity and distribution of cargoes in cells.
A sulfur molecule to block the coronavirus
Some viruses can get inside cells via a mechanism that involves sulfur organic molecules. An NCCR team has discovered effective inhibitors and blocked the uptake of SARS-CoV-2.
Cells relax their membrane to control protein sorting
NCCR Chemical Biology researchers have succeeded in measuring the tension of the membrane of an organelle forming inside a cell.
Heart attack and tissue damage: the missing link is a lipid
Major breakthrough published in Nature Metabolism today. Discovery of the molecule responsible for tissue necrosis due to an infarct, and how to reduce tissue damage by 30% in mice!
The physical forces of cells in action
Hot from the press of JACS! Mechanosensitive fluorescent probes to Image membrane tension in mitochondria, endoplasmic reticulum & lysosomes! Congrats to our NCCR groups who made it happen!
