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How a protein regulates gene expression

Prof. Beat Fierz’s group at NCCR EPFL have discovered how specialized proteins control gene expression by binding and compacting discrete parts of DNA inside the cell.

What exactly is Chemical Biology?

For its 10th anniversary, Nature Chemical Biology asked the question: “define chemical biology ?” to a panel of scientists.

Bromodomains epigenetic readers

Bromodomains are important actors in epigenetic regulation. They represent small domains of about 110 amino acids that dock onto chromatin bearing acetylated lysine histone tails.